Sequence databases

EMBL

NCBI

IMG/M

JGI Genome Portal

AntiSMASH DB ¹

• A database with an overview of the available biosynthetic gene cluster predictions. It is possible to browse the database by phylogeny or secondary metabolite type.

MIBiG ²

• Minimal information for Biosynthetic gene clusters. The Minimum Information about a Biosynthetic Gene cluster (MIBiG) contains annotations and metadata on experimentally validated biosynthetic gene clusters and their molecular products.

BIG FAM ³

• BiG-FAM is a database of thousands of gene cluster families that captures the global diversity of 1,225,071 BGCs predicted from 209,206 publicly available microbial genomes and metagenome-assembled genomes (MAGs). BiG-SLiCE is the algorithm behind BiG-FAM.

1. Kai Blin; Simon Shaw; Satria A. Kautsar; Marnix H. Medema; Tilmann Weber. (2020) The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes< em> Nucleic Acids Research , gkaa978; doi: 10.1093/nar/gkaa978
2. Satria A Kautsar, Kai Blin, Simon Shaw, Jorge C Navarro-Muñoz, Barbara R Terlouw, Justin J J van der Hooft, Jeffrey A van Santen, Vittorio Tracanna, Hernando G Suarez Duran, Victòria Pascal Andreu, Nelly Selem-Mojica, Mohammad Alanjary, Serina L Robinson, George Lund, Samuel C Epstein, Ashley C Sisto, Louise K Charkoudian, Jérôme Collemare, Roger G Linington, Tilmann Weber, Marnix H Medema, (2020) MIBiG 2.0: a repository for biosynthetic gene clusters of known function, Nucleic Acids Research, Volume 48, Issue D1, 08 January 2020, Pages D454–D458, https://doi.org/10.1093/nar/gkz882
3. Satria A Kautsar, Kai Blin, Simon Shaw, Tilmann Weber, Marnix H Medema, BiG-FAM: the biosynthetic gene cluster families database, (2021) Nucleic Acids Research, Volume 49, Issue D1, Pages D490–D497, https://doi.org/10.1093/nar/gkaa812