Streptomyces albus J1074

Streptomyces albus J1074 is commonly used as a heterologous host for production of secondary metabolites.
It makes an efficient host partially because of its fast growth and naturally minimised genome.
Its genome is one of the smallest within the Streptomyces genus, with a size of 6,841,649 bp, coding for 5,832 genes.
It has a GC content of 73.3%, one of the highest of all the streptomycetes.
S. albus J1074 has a valine- and isoleucine- auxotrophic phenotype and is defective in the SalI (SalGI) restriction-modification system, which means it can easily be genetically manipulated.

References: Zaburannyi et al. BMC Genomics 2014, 15:97

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