Genome mining tools

Actinobacteria are talented producers of secondary metabolites, many of which have useful biological activities. Thanks to the development of many targeted genome mining tools for bacteria, we can now identify previously uncharacterised biosynthetic gene clusters (BGCs) for natural products.

Some useful genome mining resources are listed below:

• antiSMASH: https://antismash.secondarymetabolites.org/#!/start

Reference: Medema, MH et al Nucleic Acids Res. 2011 Jul 1; 39 Twitter: https://twitter.com/antiSMASH_dev