Micromonospora: Difference between revisions

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=<i>Micromonospora</i>=
In the family <em>[https://en.wikipedia.org/wiki/Micromonosporaceae Micromonosporaceae]</em>, best known for making [https://en.wikipedia.org/wiki/Gentamicin gentamicin] which can be used to treat Gram-negative bacterial infections.
In the family <em>[https://en.wikipedia.org/wiki/Micromonosporaceae Micromonosporaceae]</em>, best known for making [https://en.wikipedia.org/wiki/Gentamicin gentamicin] which can be used to treat Gram-negative bacterial infections.
==Morphology==
On a plate, <i>Micromonospora</i> can be identified as red/orange/brown colonies which develop black pigmentation over time. Under the microscope, <i>Micromonospora</i> can be observed as unbranched vegetative hyphae which develop into branched reprodutive hyphae in possession of young individual sporophores<sup>[1]</sup>.
[[File:Oligo_3.png|200 px|thumb|bottom|Micromonospora colony on GYM agar]]
==Secondary metabolites==
<i>Micromonospora</i> produce a number of bioactive secondary metabolites, including the aminoglycoside gentamicin and the anticancer agent calicheamicin.
=References=
# SUAREZ, J. E. & HARDISSON, C. 1985. Morphological characteristics of colony development in Micromonospora chalcea. J Bacteriol, 162, 1342-4.

Latest revision as of 15:07, 30 August 2019

Micromonospora

In the family Micromonosporaceae, best known for making gentamicin which can be used to treat Gram-negative bacterial infections.

Morphology

On a plate, Micromonospora can be identified as red/orange/brown colonies which develop black pigmentation over time. Under the microscope, Micromonospora can be observed as unbranched vegetative hyphae which develop into branched reprodutive hyphae in possession of young individual sporophores[1].

Micromonospora colony on GYM agar

Secondary metabolites

Micromonospora produce a number of bioactive secondary metabolites, including the aminoglycoside gentamicin and the anticancer agent calicheamicin.

References

  1. SUAREZ, J. E. & HARDISSON, C. 1985. Morphological characteristics of colony development in Micromonospora chalcea. J Bacteriol, 162, 1342-4.