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Saccharopolyspora is a genus of filamentous bacteria in the family Pseudonocardiaceae along with Amycolatopsis and Pseudonocardia. Best known species is Saccharopolyspora erythraea which makes the antibiotic erythromycin.

Saccharopolyspora erythraea - known for producing erythromycin.

Saccharopolyspora spinosa - known for producing spinosyns.