From ActinoBase


In the family Micromonosporaceae, best known for making gentamicin which can be used to treat Gram-negative bacterial infections.


On a plate, Micromonospora can be identified as red/orange/brown colonies which develop black pigmentation over time. Under the microscope, Micromonospora can be observed as unbranched vegetative hyphae which develop into branched reprodutive hyphae in possession of young individual sporophores[1].

Micromonospora colony on GYM agar

Secondary metabolites

Micromonospora produce a number of bioactive secondary metabolites, including the aminoglycoside gentamicin and the anticancer agent calicheamicin.


  1. SUAREZ, J. E. & HARDISSON, C. 1985. Morphological characteristics of colony development in Micromonospora chalcea. J Bacteriol, 162, 1342-4.