Micromonospora: Difference between revisions

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=<i>Micromonospora</i>
In the family <em>[https://en.wikipedia.org/wiki/Micromonosporaceae Micromonosporaceae]</em>, best known for making [https://en.wikipedia.org/wiki/Gentamicin gentamicin] which can be used to treat Gram-negative bacterial infections.
In the family <em>[https://en.wikipedia.org/wiki/Micromonosporaceae Micromonosporaceae]</em>, best known for making [https://en.wikipedia.org/wiki/Gentamicin gentamicin] which can be used to treat Gram-negative bacterial infections.
==Morphology==
On a plate, <i>Micromonospora</i> can be identified as red/orange/brown colonies which develop black pigmentation over time. Under the microscope, <i>Micromonospora</i> can be observed as unbranched vegetative hyphae which develop into branched reprodutive hyphae in possession of young individual sporophores<sup>[1]</sup>.
==Secondary metabolites==
<i>Micromonospora</i> produce a number of bioactive secondary metabolites, including the aminoglycoside gentamicin and the anticancer agent calicheamicin.
=References=
[1] SUAREZ, J. E. & HARDISSON, C. 1985. Morphological characteristics of colony development in Micromonospora chalcea. J Bacteriol, 162, 1342-4.

Revision as of 14:52, 30 August 2019

=Micromonospora In the family Micromonosporaceae, best known for making gentamicin which can be used to treat Gram-negative bacterial infections.

Morphology

On a plate, Micromonospora can be identified as red/orange/brown colonies which develop black pigmentation over time. Under the microscope, Micromonospora can be observed as unbranched vegetative hyphae which develop into branched reprodutive hyphae in possession of young individual sporophores[1].

Secondary metabolites

Micromonospora produce a number of bioactive secondary metabolites, including the aminoglycoside gentamicin and the anticancer agent calicheamicin.

References

[1] SUAREZ, J. E. & HARDISSON, C. 1985. Morphological characteristics of colony development in Micromonospora chalcea. J Bacteriol, 162, 1342-4.