Streptomyces albus: Difference between revisions
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=<em>Streptomyces albus</em> J1074= | =<em>Streptomyces albus</em> J1074= | ||
*<em>Streptomyces albus</em> J1074 is commonly used as a heterologous host for production of secondary metabolites | *<em>Streptomyces albus</em> J1074 is commonly used as a heterologous host for production of secondary metabolites. | ||
*It makes an efficient host partially because of its fast growth and naturally minimised genome. | |||
*Its genome is one of the smallest within the <em>Streptomyces genus</em>, with a size of 6,841,649 bp, coding for 5,832 genes. | *Its genome is one of the smallest within the <em>Streptomyces genus</em>, with a size of 6,841,649 bp, coding for 5,832 genes. | ||
*It | *It has a GC content of 73.3%, one of the highest of all the streptomycetes. | ||
*<em>S. albus</em> J1074 has a valine- and | *<em>S. albus</em> J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the <em>Sal</em>I | ||
(<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated. | (<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated. |
Revision as of 18:19, 8 June 2019
Streptomyces albus J1074
- Streptomyces albus J1074 is commonly used as a heterologous host for production of secondary metabolites.
- It makes an efficient host partially because of its fast growth and naturally minimised genome.
- Its genome is one of the smallest within the Streptomyces genus, with a size of 6,841,649 bp, coding for 5,832 genes.
- It has a GC content of 73.3%, one of the highest of all the streptomycetes.
- S. albus J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the SalI
(SalGI) restriction-modification system, which means it can easily be genetically manipulated.