Streptomyces albus: Difference between revisions
From ActinoBase
No edit summary |
mNo edit summary |
||
| Line 3: | Line 3: | ||
*<em>Streptomyces albus</em> J1074 is commonly used as a heterologous host for production of secondary metabolites. | *<em>Streptomyces albus</em> J1074 is commonly used as a heterologous host for production of secondary metabolites. | ||
*It makes an efficient host partially because of its fast growth and naturally minimised genome. | *It makes an efficient host partially because of its fast growth and naturally minimised genome. | ||
*Its genome is one of the smallest within the <em>Streptomyces | *Its genome is one of the smallest within the <em>Streptomyces</em> genus, with a size of 6,841,649 bp, coding for 5,832 genes. | ||
*It has a GC content of 73.3%, one of the highest of all the streptomycetes. | *It has a GC content of 73.3%, one of the highest of all the streptomycetes. | ||
*<em>S. albus</em> J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the <em>Sal</em>I | *<em>S. albus</em> J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the <em>Sal</em>I | ||
(<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated. | (<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated. | ||
Revision as of 18:19, 8 June 2019
Streptomyces albus J1074
- Streptomyces albus J1074 is commonly used as a heterologous host for production of secondary metabolites.
- It makes an efficient host partially because of its fast growth and naturally minimised genome.
- Its genome is one of the smallest within the Streptomyces genus, with a size of 6,841,649 bp, coding for 5,832 genes.
- It has a GC content of 73.3%, one of the highest of all the streptomycetes.
- S. albus J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the SalI
(SalGI) restriction-modification system, which means it can easily be genetically manipulated.
