Streptomyces albus: Difference between revisions

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*Its genome is one of the smallest within the <em>Streptomyces</em> genus, with a size of 6,841,649 bp, coding for 5,832 genes.
*Its genome is one of the smallest within the <em>Streptomyces</em> genus, with a size of 6,841,649 bp, coding for 5,832 genes.
*It has a GC content of 73.3%, one of the highest of all the streptomycetes.
*It has a GC content of 73.3%, one of the highest of all the streptomycetes.
*<em>S. albus</em> J1074 has a valine- and isoleucine auxotrophic phenotype and is defective in the <em>Sal</em>I (<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated.
*<em>S. albus</em> J1074 has a valine- and isoleucine- auxotrophic phenotype and is defective in the <em>Sal</em>I (<em>Sal</em>GI) restriction-modification system, which means it can easily be genetically manipulated.

Revision as of 18:21, 8 June 2019

Streptomyces albus J1074

  • Streptomyces albus J1074 is commonly used as a heterologous host for production of secondary metabolites.
  • It makes an efficient host partially because of its fast growth and naturally minimised genome.
  • Its genome is one of the smallest within the Streptomyces genus, with a size of 6,841,649 bp, coding for 5,832 genes.
  • It has a GC content of 73.3%, one of the highest of all the streptomycetes.
  • S. albus J1074 has a valine- and isoleucine- auxotrophic phenotype and is defective in the SalI (SalGI) restriction-modification system, which means it can easily be genetically manipulated.