Actinobacteria are talented producers of secondary metabolites, many of which have useful biological activities. Thanks to the development of targeted genome mining tools, we can now search bacterial genomes to identify uncharacterised biosynthetic gene clusters for natural products.
Some useful genome mining tools are listed below:
Reference: Medema et al Nucleic Acids Res. 2011 Jul 1; 39 Twitter: https://twitter.com/antiSMASH_dev